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- 𩺠Cardiologist Builds Award-Winning AI Health Assistant in 7 Days
𩺠Cardiologist Builds Award-Winning AI Health Assistant in 7 Days
Inside: Physician AI app, fast pregnancy AI, exercise brain link, cancer risk score, MPN slide AI, lifelong AI Doctor

AIHealthTech Insider: Issue #89
February 23, 2026
This issue highlights physician-built AI tools, generative models accelerating biomedical research, new biological pathways linking exercise to brain health, machine-learning risk scores tied to cancer, and AI systems improving diagnostic precision in pathology.
Summaries are for education, not medical advice. Always verify locally before clinical use.
A practicing cardiologist built PostVisit.ai, an AI care platform powered by OpusāÆ4.6, in just seven days. Ranked 3rd out of 13,000 applicants, it unifies a patientās medical history, connected devices, and evidenceābased resources into one interface showing how modern AI now lets physicians independently create advanced, patientāfacing tools.

Image Source: PostVisit.ai edited with ChatGPT 5.2
Why it matters
Shows clinicians can now build full-stack health apps solo
Centralizes fragmented patient data into one AI-guided companion
Demonstrates real-world use of massiveācontext models in care
Highlights a new class of physicianābuilt agentic platforms
š Source ā PostVisit.ai
Researchers at UCSF and Wayne State used generative AI on complex pregnancy and microbiome datasets, creating prediction pipelines that matched or outperformed human teams, completing weeks of coding in minutes.

Image Source: Science Direct
Why it matters
Cuts months from medical data analysis timelines
Helps accelerate research on preterm birth, which affects ~1,000 U.S. babies daily
Reduces dependence on large, specialized data science teams
Allows researchers to focus on scientific questions instead of debugging code
š Source ā Benchmarking large language models for predictive modeling in biomedical research with a focus on reproductive health
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Do you know:šExercise may protect the brain from Alzheimerās
UCSF researchers found that exercise boosts the brain's protective barrier in aging by causing the liver to release an enzyme (GPLD1) that removes a harmful protein (TNAP) from brain blood vessels, reducing leakiness, inflammation, and improving memory in older mice.

Image Source: GPT-5.2 / AIHealthTech Insider
Why it matters
May explain how exercise lowers Alzheimerās risk
Identifies a new liver-to-brain anti-aging pathway
Shows memory decline can be reversed late in life (in mice)
Points to new drug targets beyond traditional brain-focused therapies
š Source ā Liver exerkine reverses aging- and Alzheimerās-related memory loss via vasculature
A Nature Communications study used machine learning to estimate insulin resistance from 9 routine clinical measures. In UK Biobank data, the AI-derived score (AI-IR) predicted future diabetes better than BMI and common proxies and was linked to increased risk of several cancers, including uterine, kidney, esophagus, pancreas, colon, and breast.

Image Source: GPT-5.2 / AIHealthTech Insider
Why it matters
⢠Uses routine labs to flag risk
⢠Links insulin resistance to cancer risk
⢠May refine screening beyond BMI
⢠Supports earlier prevention strategies
š Source ā Machine learning-predicted insulin resistance is a risk factor for 12 types of cancer
The LED Device Clinics Actually Use.
Not all light therapy is created equal.
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Results vary. Consistent use required.
A Leukemia study developed an AI to differentiate between prefibrotic primary myelofibrosis (prePMF) and essential thrombocythemia (ET) using digitized bone marrow images. The model achieved an AUROC of 0.89 and 92.3% accuracy in thrombocytosis cases, suggesting it detects signals beyond classic criteria, such as higher marrow fat in ET and higher cellularity in prePMF.

Image Source: Nature
Why it matters
⢠Helps separate two similar MPNs
⢠Could reduce pathologist discordance
⢠Flags adiposity/cellularity as signals
⢠May improve risk-aligned care decisions
Superpower introduced an AI Doctor designed to provide continuous healthcare by maintaining detailed records of symptoms, medication, lab trends, lifestyle, and goals. It incorporates "healthy skepticism" to flag inconsistencies between behavior and biomarker data, and offers citations and reasoning for verification.

Image Source: Superpower
Why it matters
⢠Brings continuity back to primary care
⢠Connects labs, symptoms, and habits
⢠Holds users accountable to their data
⢠Shows transparent sources and reasoning
š Source ā Superpower | AI Doctor
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